Gene information
Official symbol PIK3C2A
Official full name phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
Gene type protein-coding gene
Chromosome11p15.1
Alias symbolPI3K-C2alpha
Gene familyPhosphatidylinositol 3-kinase subunits
Resources
Entrez Gene 5286
HGNC HGNC:8971
Ensembl ENSG00000011405
Vega OTTHUMG00000166036
UCSC uc001mmq.6
GO terms: 38 records
GO Description Category LogP Number of genes Detail
GO:0003012 muscle system process GO Biological Processes -27.3938503 63 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0005543 phospholipid binding GO Molecular Functions -6.61792344 45 More
GO:0007167 enzyme-linked receptor protein signaling pathway GO Biological Processes -26.8285253 93 More
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway GO Biological Processes -16.7048742 60 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008286 insulin receptor signaling pathway GO Biological Processes -3.0699689 9 More
GO:0008289 lipid binding GO Molecular Functions -15.8223476 88 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0009896 positive regulation of catabolic process GO Biological Processes -13.5088608 63 More
GO:0010506 regulation of autophagy GO Biological Processes -5.54010569 34 More
GO:0010508 positive regulation of autophagy GO Biological Processes -4.14985165 17 More
GO:0010594 regulation of endothelial cell migration GO Biological Processes -41.8778170 72 More
GO:0010595 positive regulation of endothelial cell migration GO Biological Processes -28.3201829 45 More
GO:0010632 regulation of epithelial cell migration GO Biological Processes -42.8870194 81 More
GO:0010634 positive regulation of epithelial cell migration GO Biological Processes -29.2566722 52 More
GO:0019898 extrinsic component of membrane GO Cellular Components -2.13392265 23 More
GO:0030335 positive regulation of cell migration GO Biological Processes -66.7331035 139 More
GO:0032868 response to insulin GO Biological Processes -11.6850377 35 More
GO:0032869 cellular response to insulin stimulus GO Biological Processes -9.16399556 26 More
GO:0032870 cellular response to hormone stimulus GO Biological Processes -24.7707938 79 More
GO:0032940 secretion by cell GO Biological Processes -8.42144465 43 More
GO:0038127 ERBB signaling pathway GO Biological Processes -2.50267494 8 More
GO:0040017 positive regulation of locomotion GO Biological Processes -69.9490345 147 More
GO:0042310 vasoconstriction GO Biological Processes -9.70418585 13 More
GO:0043434 response to peptide hormone GO Biological Processes -26.1739008 69 More
GO:0043535 regulation of blood vessel endothelial cell migration GO Biological Processes -45.8916712 37 More
GO:0043536 positive regulation of blood vessel endothelial cell migration GO Biological Processes -25.0316183 33 More
GO:0046903 secretion GO Biological Processes -18.5147167 70 More
GO:0051272 positive regulation of cellular component movement GO Biological Processes -66.5150412 143 More
GO:0071375 cellular response to peptide hormone stimulus GO Biological Processes -15.9961580 44 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0090049 regulation of cell migration involved in sprouting angiogenesis GO Biological Processes -34.2220297 25 More
GO:0140352 export from cell GO Biological Processes -8.94733589 48 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
GO:2000147 positive regulation of cell motility GO Biological Processes -67.8620360 143 More
Drug-Gene interaction
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Related drugs: 15 records
Drug name Interaction type Source PMID View
alpelisib inhibitor MyCancerGenome view
apitolisib inhibitor MyCancerGenome view
buparlisib inhibitor MyCancerGenome view
copanlisib inhibitor MyCancerGenome view
dactolisib inhibitor MyCancerGenome view
gedatolisib inhibitor MyCancerGenome view
gsk-2636771 inhibitor MyCancerGenome view
infigratinib inhibitor MyCancerGenome view
pf-04691502 inhibitor MyCancerGenome view
pi-103 inhibitor MyCancerGenome view
pictilisib inhibitor MyCancerGenome view
pilaralisib inhibitor MyCancerGenome view
quercetin inhibitor MyCancerGenome view
sonolisib inhibitor MyCancerGenome view
voxtalisib inhibitor MyCancerGenome view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
PIK3C2A transcriptomics acute myocardial infarction[diagnosis] acute myocardial infarction Tan B et al. Medicine (Baltimore). 2019
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